I've been doing a lot with Django lately, and initially set it up using mod_python as the Django docs recommend, but still have some reservations about that kind of arrangement. I'd like to go back to running it under SCGI or something similar.
Django has support builtin for FastCGI, but after trying to install mod_fastcgi in my Apache 2.0.x setup, decided it was a PITA. mod_scgi is quite easy to setup in Apache (even though the documentation is mostly nonexistent). After finding where Django implements its FastCGI support using the flup module, I saw that with just a few minor tweaks Django could be made to support all of flup's protocols, including SCGI and AJP (Apache Jserv Protocol).
AJP turns out to be very interesting because it's included standard with Apache 2.2 as mod_proxy_ajp, and can work with mod_proxy_balancer - meaning you could setup multiple Django instances and have Apache share the load between them.
After testing a bit, I submitted a patch, and will probably switch to running my Django sites as AJP servers managed by daemontools, and frontended by Apache 2.2